The Cardiometabolic Prevention Centre aims to share best practices in academic preventive cardiology to assist providers when caring for their patients.
The Unmet Need
The contemporary medical therapy for patients with cardiovascular disease is complex and involves aggressive risk factor modification as well as newer pharmacologic agents including lipid lowering, diabetic, and antithrombotic agents for example.
If you are interested in launching a Cardiometabolic Prevention Clinic at your institution, please contact us at Cardiometprevention@unityhealth.to for more information.
*Coming Soon* Cardiometabolic Prevention Training Course
The Cardiometabolic Prevention Centre aims to share best practices in academic preventive cardiology by developing the following training modules. Our goal is to assist providers when caring for their patients with cardiovascular (CV) risk.
1. Risk Assessment
- Traditional CV Risk Assessment
- Understanding Risk Assessment with “Risk Enhancers” Biomarkers
- Understanding “Risk Enhancers” Imaging
- Understanding “Risk Enhancers” Sex-Specific Issues/Conditions
2. Risk Reduction
- Risk Reduction in Patients with Elevated lpa
- Uncomplicated CVD
- Risk Reduction in Uncomplicated CVD – Current Approaches to Lipid Lowering
- Risk Reduction in Patients with DM and CVD
- Risk Reduction in Patients with HT: Review of the CHEP Guidelines
3. Additional
- Risk Reduction in Higher Risk Patients with CVD or PAD – the Role of Antithrombotic Agents
- Risk Reduction in FH Patients
- Risk Reduction in Chronic kidney disease Patients
Publications
Cardiovascular Health
- Lyubarova R, et al. Metabolic syndrome cluster does not provide incremental prognostic information in patients with stable cardiovascular disease: A post hoc analysis of the AIM-HIGH trial. J Clin Lipidol. 2017 Sep-Oct;11(5):1201-1211. doi: 10.1016/j.jacl.2017.06.017. Epub 2017 Jul 5. PMID: 28807460; PMCID: PMC5612889.
- Abramson, BL. Heart Health for Canadians – The Definitive Guide. Maryam Sanati, Rick Broadhead, editor(s). Toronto (Canada): Collins, A Division of HarperCollins Publishers Ltd.; 2013.
Atherosclerosis
Troponin
- Peter A. Kavsak, et al. Analytic result variation for high-sensitivity cardiac troponin: Interpretation and consequences. Canadian Journal of Cardiology. 2023 Apr 22. https://doi.org/10.1016/j.cjca.2023.04.013.
- Peter A. Kavsak, et al. Imprecision of high-sensitivity cardiac troponin assays at the female 99th-percentile, Clinical Biochemistry, Volume 125, 2024, 110731, ISSN 0009-9120, https://doi.org/10.1016/j.clinbiochem.2024.110731.
Menopause
- Reid, R; Abramson, BL; Blake, J; Desindes, S; Dodin, S; Johnston, S; Sodhi, N; Rowe, T; Wilks, P; Wolfman, W. Managing Menopause. Journal of Obstetrics and Gynaecology Canada. 2014 Sep(September):S1-S80. 2014;36(9eSuppl A).
- Abramson BL, Black DR, Christakis MK, Fortier M, Wolfman W. Guideline No. 422e: Menopause and Cardiovascular Disease. J Obstet Gynaecol Can. 2021 Dec;43(12):1438-1443.e1. doi: 10.1016/j.jogc.2021.09.010. Epub 2021 Nov 17. PMID: 34895581.
- Srivaratharajah K, Abramson BL. Hypertension in menopausal women: the effect and role of estrogen. Menopause. 2019 Apr;26(4):428-430. doi: 10.1097/GME.0000000000001304. PMID: 30889094.
- Abramson BL, Black DR, Christakis MK, Fortier M, Wolfman W. Guideline No. 422e: Menopause and Cardiovascular Disease. J Obstet Gynaecol Can. 2021 Dec 1;43(12):1438-1443.e1.
Smoking Cessation
- Eisenberg MJ, et al. Varenicline for Smoking Cessation in Hospitalized Patients With Acute Coronary Syndrome. Circulation AHA. 2016 Jan;Circulation. 2016 Jan 5;133(1):21-30. doi: 10.1161/CIRCULATIONAHA.115.019634.
- Windle SB, et al. Smoking abstinence 1 year after acute coronary syndrome: follow-up from a randomized controlled trial of varenicline in patients admitted to hospital. CMAJ. 2018 Mar 26;190(12):E347-E354. doi: 10.1503/cmaj.170377. PMID: 29581161; PMCID: PMC5871438.
- Dehghani P, et al. Smokers and Postcessation Weight Gain After Acute Coronary Syndrome. J Am Heart Assoc. 2017 Apr 18;6(4):e004785. doi: 10.1161/JAHA.116.004785. PMID: 28420644; PMCID: PMC5532997.
Pregnancy
Hypertension
- Abramson BL, Melvin RG. Cardiovascular risk in women: focus on hypertension. Can J Cardiol. 2014 May;30(5):553-9. doi: 10.1016/j.cjca.2014.02.014. Epub 2014 Feb 26. PMID: 24786446.
- Beth L. Abramson, Daniel Esau. Blood Pressure: Changes Over a Woman’s Life, the Effect of Estrogen, and Special Considerations in Women. In: Lorrie Kirshenbaum, Inna Rabinovich-Nikitin,
editor(s). Biology of Women’s Heart Health. 1. 26. Springer Cham; 2023. p. 107-129. - Abramson, BL, Srivaratharajah, K, Davis, L, Parapid, B. Women and Hypertension: Beyond the 2017 Guideline for Prevention, Detection, Evaluation, and Management of High Blood Pressure in Adults. American College of Cardiology. 2018 Sep.
Peripheral Artery Disease
- Beth L. Abramson, Mohammed Al Oran, Sonia S. Anand, et al. Canadian Cardiovascular Society 2022 Guidelines for Peripheral Arterial Disease. Canadian Journal of Cardiology. 2022 May;38(5):560-587. doi.org/10.1016/j.cjca.2022.02.029.
- Berger, JS; Abramson, BL; et al. Ticagrelor versus Clopidogrel in Patients with Symptomatic Peripheral Artery Disease and Prior Coronary Artery Disease: Insights from the EUCLID Trial. Journal of Vascular Medicine. 2018 Mar. VMJ-18-2985.R1.
- Srivaratharajah K, Abramson BL. Women and Peripheral Arterial Disease: A Review of Sex Differences in Epidemiology, Clinical Manifestations, and Outcomes. Can J Cardiol. 2018 Apr;34(4):356-361. doi: 10.1016/j.cjca.2018.01.009. Epub 2018 Jan 31. PMID: 29571419.
- Abramson, BL; Huckell, V; Dziarmaga, A; Chayab, L. Establishing the Canadian Prevalence of Asymptomatic Peripheral Artery Disease in Subjects with Moderate Cardiovascular Disease Risk
Factors. Canadian Medical American Journal. 2012. - Abramson BL, Al-Omran M, Anand SS, et al. Canadian Cardiovascular Society 2022 Guidelines for Peripheral Arterial Disease. Can J Cardiol. 2022 May 1;38(5):560-587.
Sex and Gender
- Srivatharaja, K; Abramson BL. Sex Differences in Cardiac Diseases: Niti Aggarwal; Malissa Wood, editor(s). Pathophysiology, Presentation, Diagnosis and Management. eBook ISBN: Published Date: 26th January 2021 Chapter 19. Toronto: Elsevier, Perpheral Arterial Disease; 2021.
- Mody, P; Pandy, A; Slutsky, A; Segar, M; Kiss, A; Dorian, P; Parsons, J; Scales, D; Rac, V; Cheskes, S; Bierman, A; Abramson, B; Gray, S; Fowler, R; Dainty, K; Idris, A; Morrison, L. Gender Based Differences in Outcomes among Resuscitated Patients with Out-of-Hospital Cardiac Arrest. Circulation. 2020 Dec.
- Morrison LJ, Schmicker RH, Weisfeldt ML, Bigham BL, Berg RA, Topjian AA, Abramson BL, Atkins DL, Egan D, Sopko G, Rac VE; Resuscitation Outcomes Consortium Investigators. Effect of gender on outcome of out of hospital cardiac arrest in the Resuscitation Outcomes Consortium. Resuscitation. 2016 Mar;100:76-81. doi: 10.1016/j.resuscitation.2015.12.002. Epub 2015 Dec 17. PMID: 26705971; PMCID: PMC4761304.
- Abramson, BL, Srivaratharajah, K. Identifying and Managing Younger Women at High Risk of Cardiovascular Disease. Canadian Medical Association Journal. 2019 Feb;CMAJ 2019 February 11;191:E159-63. doi: 10.1503/cmaj.180053. Available from: www.cmaj.ca/lookup/doi/10.1503/cmaj.180053.
- Rodriguez de Morales YA, Abramson BL. Cardiovascular and physiological risk factors in women at mid-life and beyond. Can J Physiol Pharmacol. 2024 Aug 1;102(8):442-451. doi: 10.1139/cjpp-2023-0468. Epub 2024 May 13. PMID: 38739947.
- Srivaratharajah K, Abramson BL. Identifying and managing younger women at high risk of cardiovascular disease. CMAJ. 2019 Feb 11;191(6):E159-E163. doi: 10.1503/cmaj.180053. PMID: 30745400; PMCID: PMC6370542.
Diabetes
Ischemic Heart Disease
Training and Education
- Adreak N, Srivaratharajah K, Mullen KA, Pike A, Mackay MH, Comber L, Abramson BL. Incorporating a Women’s Cardiovascular Health Curriculum Into Medical Education. CJC Open. 2021 Sep 28;3(12 Suppl):S187-S191. doi: 10.1016/j.cjco.2021.09.020. PMID: 34993448; PMCID: PMC8712710.
- Abramson, B. WIC International Perspective: A Canadian Cardiologist Who Has Stuck to Her Roots. American College of Cardiology. 2021 Jun; Women in Cardiology.
- Najah Adreak, et al. Integration of Women’s Cardiovascular Health Content Into Healthcare Provider Education: Results of a Rapid Review and National Survey. CJC Open. 2024 Feb;6(2, Part B):463-472.